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  • Diabetes insipidus results in excessive drinking and urination. As many conditions cause these signs, a number of diagnostic tests including bloodwork and urinalysis need to be performed to rule out other causes. After more common causes are ruled out, a modified water deprivation test can confirm disease and an MRI or therapeutic trial can be performed. Diabetes insipidus results from reduced production of ADH from the brain or reduced sensitivity to ADH in the kidney. Treatment depends on the cause of the disease either replacing the lack of ADH with a synthetic replacement or using a hydrochlorothiazide and a low salt diet to decrease urine production.

  • Diabetes is an inability of the body to regulate blood sugar caused by an abnormality of the pancreas. It causes increased thirst, urination, appetite, and weight loss. Most dogs have type 1 diabetes, caused by total or near destruction of the insulin-producing cells, and insulin injections are required for treatment. Diabetes is diagnosed by measuring increased levels of glucose in the urine and blood. Diabetes treatment includes insulin injections and dietary manipulation with regular blood sugar monitoring. Financial costs can be high during the regulation period, or if a complication arises, and twice-daily insulin injections are a lifelong commitment.

  • Diabetes mellitus results from an inadequate production of insulin from the pancreas. The primary treatment is replacement by insulin injections. The body's response to the injections needs to be regularly monitored using an at-home glucometer or continuous glucose monitoring system. Insulin must be stored and reconstituted carefully to ensure dosing is accurate. Giving subcutaneous injections of insulin can seem daunting at first, but by following the directions in this handout, it will quickly become second nature to both you and your pet.

  • Diabetes mellitus is an inability to regulate blood glucose caused by a loss of insulin production (Type I) or inadequate insulin supply or resistance (Type II). Dogs need insulin injections to manage diabetes. Sometimes special diets may help manage the disease. Response to insulin needs to be monitored to ensure adequate dosing and to avoid hypoglycemia caused by insulin overdose. Blood glucose curves are most commonly used for this including: in-clinic blood glucose curves, home glucose curves with hand-held glucometers and continuous glucose monitoring systems. Urine glucose testing and fructosamine testing may also be used to manage the disease. Hypoglycemia is the consequence of administering too much insulin compared to the amount of food ingested. Signs can range from lethargy to seizures and coma. It can be managed acutely with administration of sugar syrup to the gums but more severely affected dogs will need IV dextrose solutions.

  • Diabetic ketoacidosis is a medical emergency that occurs when there is not enough insulin in the body to control blood sugar (glucose) levels. It is important for your veterinarian to perform appropriate tests in order to diagnose this disease as similar signs can occur with other medical conditions. Treatment involves hospitalization with IV fluids, short acting insulin and electrolyte replacement. The most important step in prevention is ensuring proper insulin dosing is being administered.

  • Diarrhea is a symptom of an underlying problem that may be minor or very serious. Some cases may resolve on their own or with minimal treatment, while other cases require in-depth diagnostic testing and more aggressive treatment to address the underlying condition. The possible causes, diagnostic tests, and treatment protocols for diarrhea in dogs are numerous and are explained in this handout.

  • If your dog is having diarrhea, please complete this questionnaire as accurately as possible before your appointment. This information will be very helpful to your veterinarian in determining the cause of diarrhea.

  • Dilated cardiomyopathy (DCM) is a serious and often fatal condition in medium to larger breed dogs. Signs may be sudden or progressive in onset. Some signs include rapid breathing, increased effort with breathing, restless sleeping, coughing, or gagging, among others. Early and proper diagnosis is key, followed by treatment to give the best quality of life.

  • Discoid Lupus Erythematosus (DLE) is an autoimmune condition that causes skin sloughing particularly around the nose causing scabbing and erosions that can become infected with bacteria. It can also affect the ear flaps, genitals and rarely spread through the entire body. DLE is diagnosed by submitting skin biopsies of affected areas for histopathological analysis. As well as antibiotics to treat secondary bacterial infections, treatment involves suppression of the immune system including tacrolimus or steroid ointments/creams applied to the affected area. Some dogs will need tetracycline and niacinamide or stronger anti-inflammatories such as cyclosporine or corticosteroids. These treatments can be weaned once lesions resolve but flare-ups will likely occur, needing rechecks and repeat therapy. Sun exposure must be minimized as UV light can worsen the disease. If untreated, lesions can develop into squamous cell carcinoma.

  • Discospondylitis is a bacterial or fungal infection of the intervertebral disks and the adjacent vertebral bones. It primarily affects dogs, though rarely can affect cats. It affects large breed dogs more often and generally starts clinically as back pain. The diagnosis and treatment of this condition are outlined in this handout.